Introduction

ComfortanSolution for Injection

ComfortanSolution for Injection is a veterinary medication used for dogs and cats. It contains methadone, which is a powerful analgesic and tranquilizer. It’s typically used for pain relief and as a premedication for general anesthesia

• Indications: Analgesia in dogs and cats, premedication for general anesthesia or neuroleptanalgesia in combination with a neuroleptic drug.

• Contraindications: Should not be used in animals with advanced respiratory failure, severe liver and renal dysfunction, or known hypersensitivity to methadone.

• Special Precautions: Methadone may cause respiratory depression and should be used with caution in animals with impaired respiratory function. Regular monitoring of heart rate and respiratory rate is recommended.

• Pharmacokinetics: Methadone is rapidly absorbed following intramuscular injection, with a high bioavailability. It has a large volume of distribution and is extensively protein-bound.

Key Features

• Active Ingredient: Contains methadone, a potent analgesic and tranquilizer.

• Indications: Used for pain relief in dogs and cats, and as premedication for general anesthesia.

• Administration: Can be administered by intramuscular or intravenous injection.

• Onset and Duration: Rapid onset of action with long-lasting effects.

• Dosage: Specific dosage varies based on the animal’s weight and condition; always follow veterinary guidelines.

• Safety Precautions: Regular monitoring of heart rate and respiratory rate is recommended, especially in animals with respiratory, liver, or kidney issues.

• Bioavailability: High bioavailability when injected intramuscularly.

• Metabolism and Excretion: Extensively metabolized in the liver and excreted via urine.

legal category: POM-V (Prescription Only Medicine – Veterinarian) and is classified as a CD (Sch 2) (Controlled Drug, Schedule 2)

CD (Sch 2) (Controlled Drug, Schedule 2): This indicates that Comfortan is a controlled substance with strict regulations due to its potential for abuse and dependency. It must be stored securely, and records of its use must be meticulously maintained.